Decaren 60mg Capsule

Composition of Decaren 60mg Capsule

Coenzyme Q 10

Uses of Decaren 60mg Capsule

• Nutritional deficiencies

Side Effects of Decaren 60mg Capsule

Common side effects include stomach upset, loss of appetite, nausea, vomiting, and diarrhea. Some people may experience allergic skin rashes.

How does Decaren 60mg Capsule work?

Decaren 60 is a vitamin-like substance that provides essential nutrients.

Quick Suggestions:

• Acts as a natural catalyst for the release of energy from food, aiding in cellular respiration and ATP production.
• Protects the body against free radical damage with its antioxidant properties, helping to prevent oxidative stress and cellular damage.
• Acts as an adjuvant therapy in cardiovascular diseases, particularly beneficial for angina and congestive heart failure (CHF).
• Helps maintain heart health by improving energy production in heart cells and protecting them from oxidative damage.
• Helps boost the immune system, preventing immune system depression and enhancing the body's natural defense mechanisms.
• Supports cognitive function and may help slow cognitive decline, protecting brain cells from oxidative stress.
• Useful in the management of periodontal (gum) disease, promoting healthier gums and reducing inflammation.
• An intensive moisturizer that fights visible skin lines and wrinkles, helping to keep skin moisturized and reducing the appearance of aging.
• Addresses HMG CoA reductase inhibitor (statin) mediated decreased levels of Coenzyme Q10 in the blood, countering the side effects of statin drugs.
• Helps manage drug-induced myopathy, providing relief from muscle pain and weakness associated with certain medications.
• Enhances exercise performance by improving muscle energy production and reducing fatigue.

Indications:

Decaren 60 is a medicine used in the treatment of nutritional deficiencies. It has good antioxidant properties and a number of other health benefits. 

Pharmacology

Coenzyme Q10, also known as Ubidecarenone, is a fat-soluble substance that acts as a vital intermediate in the electron transport system within the mitochondrial membrane for cellular respiration and ATP production. It is present in every cell of the body, with the highest requirements in metabolically active tissues like the heart, immune system, skeletal muscle, and gingiva. It helps produce energy and has antioxidant properties.

Dosage & Administration:

Dosage recommendations vary based on the condition being treated:

• Co-enzyme Q10 deficiency: 150 mg daily.
• Mitochondrial disorders: 150-160 mg, or 2 mg/kg/day.
• Heart failure in adults: 100 mg per day divided into 2 or 3 doses.
• Recent myocardial infarction: 120 mg daily in 2 divided doses.
• High blood pressure: 120-200 mg per day divided into 2 doses.
• Isolated systolic hypertension: 60 mg twice daily.
• Preventing migraine headache: 100 mg three times daily.
• Parkinson's disease: 300 mg, 600 mg, 1200 mg, and 2400 mg per day in 3-4 divided doses.
• Infertility in men: 200-300 mg per day.
• Muscular dystrophy: 100 mg per day.

Taking smaller amounts two or three times a day instead of a large dose at once can help reduce side effects.

Coenzyme Q10 may interact with:

• Statins: Can reduce endogenous synthesis of CoQ10; supplementation may increase levels without affecting statin efficacy.
• Warfarin: May reduce the effectiveness of warfarin.
• Beta-blockers: Particularly propranolol, which may inhibit some CoQ10-dependent enzymes.
• Antidiabetic medications: May improve glycemic control in some type II diabetics; dose adjustments may be necessary.
• Doxorubicin: May help ease the cardiotoxicity of doxorubicin.

Contraindications

Coenzyme Q10 is contraindicated in patients with hypersensitivity to the active substance or any of the excipients. It should not be used in patients scheduled for surgery within the next two weeks.

Pregnancy & Lactation

Coenzyme Q10 should not be used during pregnancy and breastfeeding unless prescribed by a healthcare provider.

Precautions & Warnings

Coenzyme Q10 may lower blood sugar levels, so caution should be taken in patients with diabetes or hypoglycemia. It may also decrease blood pressure, so caution is advised in patients with low blood pressure or those taking blood pressure medications.

Storage:

• Keep in a dry place away from light and heat.
• Keep out of the reach of children.